RADIESSE® vs. Sculptra®: Answers to Your FAQs

Gently smiling mature woman (model)

Today’s facial rejuvenation options are moving beyond simply filling fine lines to biostimulation: treatments that trigger the body’s natural ability to restore itself. RADIESSE and Sculptra are two popular options that encourage collagen production for longer-lasting, natural-looking improvements. So, what are the similarities and differences between these two products? Find out below!

1. What’s the difference between Sculptra and RADIESSE?

Sculptra gradually restores volume by stimulating collagen over time, while RADIESSE provides immediate lift and contour with added collagen stimulation. Sculptra contains poly-L-lactic acid (PLLA), which gradually stimulates collagen for subtle, long-lasting results. RADIESSE utilizes calcium hydroxylapatite (CaHA) microspheres, which provide immediate lift while also stimulating collagen growth over time.

2. Which areas respond best to RADIESSE or Sculptra?

I typically recommend RADIESSE for areas that would benefit most from structure and lift, such as the cheeks, jawline, and nasolabial folds and Sculptra for restoring facial volume. Sculptra is particularly useful for addressing hollowing in the temples or midface.

3. Can RADIESSE or Sculptra be used for the neck?

Yes, both RADIESSE and Sculptra can rejuvenate areas beyond the face, including the neck. In some cases, RADIESSE can be diluted with saline and lidocaine—a technique called “hyperdilute RADIESSE“—to act as a skin-strengthening solution. Instead of adding bulk, this treatment stimulates the production of collagen and elastin to enhance firmness, thickness, and overall skin quality.

Sculptra, on the other hand, is frequently chosen for crepiness or skin laxity because it works gradually and evenly to restore smoothness. The choice between RADIESSE and Sculptra for neck rejuvenation typically depends on the degree of neck aging and your specific skin concerns.

4. How long do the results last?

Sculptra results can last up to 2 years or more after a series of injections, and RADIESSE typically lasts 12 to 18 months before a maintenance injection is recommended. Lifestyle factors such as skincare, sun exposure, and overall health also play a role in determining how long the results last.

5. Which is better: RADIESSE or Sculptra?

Both injectables can deliver safe, flattering results. The choice between them is less about the “better” overall option and more about which one is better for your unique needs. RADIESSE is great for patients seeking a single treatment that provides an immediate lift with ongoing collagen stimulation.

Sculptra, meanwhile, is ideal for patients who want more subtle, progressive results and are willing to commit to 2 to 3 initial sessions to achieve their desired look.

For many patients, a combination approach offers the most balanced and natural outcome by leveraging the unique strengths of each product.

6. How do RADIESSE and Sculptra compare for people with busy lifestyles?

RADIESSE is often preferred by patients who want immediate results in a single session, while Sculptra requires a series of treatments that gradually build lasting improvement. Both minimize the need for frequent touch-ups, which is why they’re especially popular among professionals in Washington, DC, who want to stay refreshed without interrupting their busy routines.

Explore Your Facial Rejuvenation Options

Whether you desire immediate contouring, gradual rejuvenation, or a combination of both, my team and I are here to create a personalized plan that helps you achieve natural, lasting results. Ready to get started? Request a consultation using the online form or call my office at (202) 393-7546.

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